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JAYPEE JOURNALS
International Scientific Journals from Jaypee
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1.  ORIGINAL ARTICLE
Platelet-rich Fibrin Influences on Proliferation and Migration of Human Gingival Fibroblasts
Hao TT Nguyen, My TN Nguyen, Van NL Trinh, Thuy AV Pham, Nga Y Tran, Ha LB Tran
[Year:2016] [Month:July-December] [Volume:5 ] [Number:2] [Pages:68] [Pages No:83-88] [No of Hits : 518]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1131 | FREE

ABSTRACT

Aims: Our study focused on the fabrication of platelet-rich fibrin (PRF) and evaluated its influences on cell behaviors, including proliferation and migration.

Materials and methods: Platelet-rich fibrin was prepared from human peripheral blood according to Choukroun’s method without using nonanticoagulant and foreign factors for platelet activation. Platelet-rich fibrin architecture was studied by hematoxylin and eosin staining. The investigation of PRF effects on human gingival fibroblasts (hGFs) was conducted via PRF liquid extract. Cell proliferation was determined via the number of cells after a period of time incubated in PRF liquid extract. Influence of PRF liquid extract on the migration of hGFs was conducted via scratch wound healing assay.

Results: Histological staining reviewed the natural fibrin fiber matrix of PRF. Platelet-rich fibrin liquid extract promoted hGF proliferation after 7 days of cultivation. Human gingival fibroblast proliferation in PRF liquid extract was more superior than those cultured in complete medium. Platelet-rich fibrin was also found to be able to promote the migration of hGFs for up to 48 hours.

Conclusion: These results indicated that PRF is suitable to be used as autologous natural biomaterial in supporting wound healing and in further application in periodontitis treatments.

Keywords: Gingival fibroblast, Migration, Periodontitis treatment, Platelet-rich fibrin, Proliferation.

How to cite this article: Nguyen HTT, Nguyen MTN, Trinh VNL, Tran NY, Ngo LTQ, Pham TAV, Tran HLB. Platelet-rich Fibrin Influences on Proliferation and Migration of Human Gingival Fibroblasts. Int J Experiment Dent Sci 2016;5(2):83-88.

Source of support: Nil

Conflict of interest: None

 
2.  CASE REPORT
Third Molar Socket Grafting after Surgical Extraction to prevent Periodontal Pocket Formation
Mohammed Jasim Aljuboori, Rajiv Saini, Ng Ying Yi
[Year:2015] [Month:January-June] [Volume:4 ] [Number:1] [Pages:76] [Pages No:65-68] [No of Hits : 1420]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1098 | FREE

ABSTRACT

There is an incidence of periodontal pocket formation and gingival recession on the distal of the lower second molar due to bone defect after third molar surgical removal. Patient referred suffering from recurrent pericoronities; after clinical and radiographic examination, the lower left 3rd molar is partially erupted and angulated in mesial direction. The radiograph shows there is bone deficiency on the distal of the adjacent 2nd molar. After 3rd molar surgical removal, cancellous bone graft placed on the socket with guided bone regeneration (GBR) procedure and complete primary closure with rotational flap. Patient follow-up after 3 and 6 months, bone formation observed on the distal of 2nd molar with the absence of periodontal pocket. Third molar socket bone grafting with cancellous allograft may be a predictable procedure to prevent periodontal pocket on the distal of the second molar.

Keywords: Third molar, Bone grafting, Guided bone regeneration, Periodontal pocket, Surgical tooth removal.

How to cite this article: Aljuboori MJ, Saini R, Yi NY. Third Molar Socket Grafting after Surgical Extraction to prevent Periodontal Pocket Formation. Int J Experiment Dent Sci 2015;4(1):65-68.

Source of support: Nil

Conflict of interest: None

 
3.  ORIGINAL ARTICLE
A Prospective Experimental Comparative Study on the Clinical Effects of Calculus Dissolution based Oral Rinse in Gingivitis Patients
Rajiv Saini
[Year:2015] [Month:January-June] [Volume:4 ] [Number:1] [Pages:76] [Pages No:33-39] [No of Hits : 1304]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1092 | FREE

ABSTRACT

Aim: The present study was aimed to evaluate the efficacy of calculus/tartar dissolution based oral rinse as an adjunct to toothbrushing in gingivitis patients for long-term effects on new supragingival calculus formation.

Materials and methods: After undergoing a dental prophylaxis, 60 gingivitis subjects with a moderate rate of calculus formation were stratified and randomly assigned to one of two groups: Control group (regular dentifrice alone) and experimental group (using a regular dentifrice and a calculus/tartar control mouthrinse). Subjects brushed and rinsed twice daily, unsupervised, for 6 months. All subjects were assessed with gingival index (GI), plaque index (PI) and calculus levels using the Volpe-Manhold Index (VMI) after 3 and 6 months.

Results: Statistical analysis found that the experimental group (which used a calculus/tartar contain mouthrinse) demonstrated statistically significantly lower VMI scores (p = 0.001) than control group (which used a regular dentifrice alone). In experiment test group A, there was decline in VMI score from 3 to 6 months by 23.12% as compared to group B where there was continuous increase in VMI scores from 3 to 6 months by 22.16%.

Conclusion: A mouthrinse containing tetrapotassium pyrophosphate and sodium tripolyphosphate as the anticalculus agent provides a clinically relevant reduction in calculus formation in subjects with a moderate rate of such formation.

Keywords: Anticalculus, Antitartar, Mouthrinse, Calculus.

How to cite this article: Saini R. A Prospective Experimental Comparative Study on the Clinical Effects of Calculus Dissolution based Oral Rinse in Gingivitis Patients. Int J Experiment Dent Sci 2015;4(1):33-39.

Source of support: Nil

Conflict of interest: None

 
4.  REVIEW ARTICLE
Fibrin Sealant: A Review of Its Applications in Periodontal Surgery
Shaju Jacob, Sonia Nath
[Year:2015] [Month:January-June] [Volume:4 ] [Number:1] [Pages:76] [Pages No:40-46] [No of Hits : 1154]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1093 | FREE

ABSTRACT

Aim: Fibrin sealant is a biological tissue adhesive mimicking the final stage of coagulation. It has a wide variety of application in the field of periodontics. The aim of this article was to review current applications and identify potential use of fibrin sealant in periodontal surgical procedures on an evidence-based conclusion.

Materials and methods: An online search was performed in PubMed, Google Scholar and Cochrane Library databases using keywords fibrin sealant, fibrin glue, fibrin, regeneration, wound healing, tissue adhesive, gingival recession/therapy, surgical therapy, periodontal, and periodontitis in a mutually inclusive manner. The studies were evaluated by two independent reviewers for inclusion in this literature review.

Results: Out of 196 research papers identified, 59 articles were selected by the authors for this literature review, giving preference to clinical trials related to periodontal application.

Conclusion: Use of fibrin sealant is a simple, safe, costeffective, and rapid way to fix flaps and grafts avoiding any postoperative bleeding. Fibrin sealant has the property for regeneration when used in conjunction with a barrier membrane for formation of new connective tissue attachment. It is effective in microsurgical procedures and closing flaps around implant site. They initiate early wound healing through collagen synthesis and fibroblast proliferation. Fibrin sealant may be an alternate biomaterial for periodontal surgery which may stimulate periodontal wound healing and regeneration.

Keywords: Fibrin glue, Periodontal flap surgery, Regeneration, Tissue adhesive, Wound healing.

How to cite this article: Jacob S, Nath S. Fibrin Sealant: A Review of Its Applications in Periodontal Surgery. Int J Experiment Dent Sci 2015;4(1):40-46.

Source of support: Nil

Conflict of interest: None

 
5.  RESEARCH ARTICLE
Anterior Middle Superior Alveolar Nerve Block Efficacy Utilizing different Anesthetic Solutions, Reduced Dosage and Conventional Syringe: A Breakthrough in Pain Control
Mustafa Tattan, Vladimir Kokovic
[Year:2015] [Month:July-December] [Volume:4 ] [Number:2] [Pages:68] [Pages No:80-86] [No of Hits : 773]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1102 | FREE

ABSTRACT

Introduction: For over a decade of introducing the anterior middle superior alveolar (AMSA) injection, it has since majorly only been reported to show both pulpal and buccal mucosal effectiveness using a minimum of 0.9 ml of anesthetic solution.

Aim: The aim of this study was to demonstrate the AMSA nerve block efficacy using a reduced dosage and conventional syringe, while comparing the anesthetic effectiveness of lidocaine vs mepivacaine. A primary objective was to understand the behavioral difference between the two solutions, to better adapt their application into relevant clinical scenarios, where fewer injections are administered, pain control is better understood and implemented, and collateral anesthesia altering the natural lip line is eliminated.

Materials and methods: Twelve candidates (both sexes), of ages 18 to 24, were selected. All the participants received bilateral AMSA nerve block (split-mouth technique) using the conventional syringe, where 0.6 ml of lidocaine and mepivacaine 2% with epinephrine 1:100,000 were randomly administered to each side.

Results: Pulpal anesthesia on both premolar teeth showed 83.3% success within 15 minutes with lidocaine group (LG) and mepivacaine group (MG) alike. Buccal anesthesia at both premolar teeth showed 50% success within 15 minutes with LG and 54.2% with MG. There was no difference in anesthetic effectiveness between the two groups in pulpal anesthesia (p ≥ 0.05), and no significant difference in buccal mucosal anesthesia (p ≥ 0.05).

Conclusion: No statistically significant difference was observed between lidocaine and mepivacaine, while both expressed anesthetic effectiveness using a reduced dosage, as well as near painlessness using the conventional syringe.

Keywords: Anterior middle superior alveolar nerve block, Buccal mucosal anesthesia, Dental research, Lidocaine, Mepivacaine, Pulpal anesthesia.

How to cite this article: Tattan M, Kokovic V. Anterior Middle Superior Alveolar Nerve Block Efficacy Utilizing different Anesthetic Solutions, Reduced Dosage and Conventional Syringe: A Breakthrough in Pain Control. Int J Experiment Dent Sci 2015;4(2):80-86.

Source of support: Nil

Conflict of interest: None

 
6.  CASE REPORT
Esthetic Rehabilitation of Mutilated Anterior Teeth with Custom Cast Post and Core Porcelain-Fused-to-Metal Crowns
Virender Singh Legha, Dinesh Kumar Saini, KV Arun Kumar
[Year:2015] [Month:January-June] [Volume:4 ] [Number:1] [Pages:76] [Pages No:69-71] [No of Hits : 658]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1099 | FREE

ABSTRACT

An endodontically treated anterior tooth requires extracoronal restoration when the tooth structure is weakened or lost due to caries, endodontic treatment, placement of previous restorations and/or is discolored. The reduced tooth structure makes retention of extracoronal restoration difficult. The purpose of post is to provide retention for the core restoration, which replaces lost coronal structure. This article describes restoration of mutilated maxillary central incisors by using cast post and core, followed with porcelain fused to metal restorations.

Keywords: Cast post and core, Esthetics, Endodontic, Porcelain-fused-to-metal.

How to cite this article: Legha VS, Saini DK, Kumar KVA. Esthetic Rehabilitation of Mutilated Anterior Teeth with Custom Cast Post and Core Porcelain-Fused-to-Metal Crowns. Int J Experiment Dent Sci 2015;4(1):69-71.

Source of support: Nil

Conflict of interest: None

 
7.  CASE REPORT
A Novel Technique to restore Anterior Esthetics with Cast Partial Denture
Bala Saraswati Bhat, Deeksha Sharma, Himanshu Arora
[Year:2015] [Month:January-June] [Volume:4 ] [Number:1] [Pages:76] [Pages No:62-64] [No of Hits : 577]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1097 | FREE

ABSTRACT

Purpose: To overcome the dilemma of fabricating a cast partial denture in patient with missing maxillary anterior teeth.

Materials and methods: A round rest distal depression clasp is used as an esthetic alternative to a conventional clasp for maxillary anterior teeth serving as abutments for a removable partial denture.

Keywords: Maxillary anterior edentulous area, Round rest distal depression clasp, Esthetic cast partial denture.

How to cite this article: Bhat BS, Sharma D, Arora H. A Novel Technique to restore Anterior Esthetics with Cast Partial Denture. Int J Experiment Dent Sci 2015;4(1):62-64.

Source of support: Nil

Conflict of interest: None

 
8.  ORIGINAL ARTICLE
Relationship between Obesity and Periodontal Status in Vietnamese Patients: A Pilot Study
Thuy Anh Vu Pham, Xuan Ngoc Thi Nguyen
[Year:2015] [Month:July-December] [Volume:4 ] [Number:2] [Pages:68] [Pages No:119-123] [No of Hits : 554]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1109 | FREE

ABSTRACT

Objectives: To investigate periodontal status and the relationship between obesity and periodontal status in female patients who first visited the Traditional Medicine Institute, Ho Chi Minh city, Vietnam.

Materials and methods: One hundred and three female patients aged 18 or older, including 45 obese subjects and 58 nonobese subjects were enrolled in a period of 5 months from February to June 2014. The information on sociodemographic characteristics and dental habits were collected by questionnaire. Periodontal status [plaque index (PI1), gingival index (GI), bleeding on prabing (BOP), pocket depth (PD), clinical attachment level (CAL)] was examined and the anthropometric index was measured.

Results: There was significantly higher prevalence of periodontitis (40.0%) in obese females than nonobese females (13.8%). The means values of periodontal parameters in obese females were significantly higher than those in nonobese females. Significantly, higher percentage of subjects who did not use dental flossing, or less regularly visited dental offices, or less regularly had their teeth scaled and polished was in the obese group than those in the nonobese group. Multiple logistic regression analysis revealed that age [odds ratio (OR = 3.60)], routine of dental visit (OR = 3.75) and obesity (OR = 3.46) were significantly related to periodontitis.

Conclusion: Periodontal status in obese subjects was poorer than nonobese ones. Obesity, age and dental visit were associated with periodontitis in Vietnamese female patients.

Keywords: Body mass index, Obesity, Periodontitis.

How to cite this article: Pham TAV, Nguyen XNT. Relationship between Obesity and Periodontal Status in Vietnamese Patients: A Pilot Study. Int J Experiment Dent Sci 2015;4(2): 119-123.

Source of support: Nil

Conflict of interest: None

 
9.  Review Article
Molar Incisor Hypomineralization
Navroop Kaur Bajwa, Mahesh Madhukar Jingarwar, Anuradha Pathak
[Year:2014] [Month:January-June] [Volume:3 ] [Number:1] [Pages:58] [Pages No:37-40] [No of Hits : 2416]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1066 | FREE

ABSTRACT

Developmental defects of tooth enamel are not uncommon, both in the primary and permanent dentition. An example of idiopathic enamel defect is molar incisor hypomineralization (MIH). The condition is defined as a hypomineralization of systemic origin of one to four permanent first molars frequently associated with affected incisors. The prevalence of MIH is reported to vary between 2.4 and 40.2% in normal child populations. Management consists of early diagnosis, prevention of caries or posteruptive breakdown and interception if caries or breakdown has already ensued. Management challenges include difficulty in obtaining adequate anesthesia, increased incidence of caries, early pulpal involvement and gross destruction of clinical crown of affected teeth. In young permanent teeth, semipermanent crowns like stainless steel crowns for posterior teeth and direct composite veneering for anterior teeth are the recommended solutions.

Keywords: Molar incisor hypomineralization, Dioxins, Cheesy molars.

How to cite this article: Bajwa NK, Jingarwar MM, Pathak A. Molar Incisor Hypomineralization. Int J Experiment Dent Sci 2014;3(1):37-40.

Source of support: Nil

Conflict of interest: None declared

 
10.  Research Articles
Comparing Shear Bond Strength of Two Step vs One Step Bonding Agents on Ground Enamel and Dentin: An in vitro Study
Darshan Deepak Shah, Manoj Chandak, Narendra Manwar, Shubhangi Mani, Ameet Mani, Rajiv Saini, Rushabh Malde
[Year:2014] [Month:January-June] [Volume:3 ] [Number:1] [Pages:58] [Pages No:1-3] [No of Hits : 1943]
Full Text PDF | Abstract | DOI : 10.5005/jp-journals-10029-1058 | FREE

ABSTRACT

Aim: To compare the shear bond strength of Tetric N Bond (Ivoclar Vivadent) and Single Bond Universal Adhesive (3M ESPE, MN, USA) on ground enamel and dentin.

Materials and methods: A total of 30 extracted human maxillary and mandibular molars and premolars were used for this study and divided into two groups which were treated with Tetric N Bond (Ivoclar Vivaden) t- and Single Bond Universal Adhesive (3M ESPE, MN, USA). The shear bond strength was tested on Universal testing machine (Instron).

Results: There was statistically significant difference in the shear bond strength among the two groups.

Conclusion: Based on the results (Tetric N Bond, Ivoclar Vivadent) had higher bond strength than Single Bond Universal Adhesive (3M ESPE, MN, USA) on ground enamel and dentin.

Keywords: Shear bond strength, Tetric N bond, Single bond universal adhesive.

How to cite this article: Shah DD, Chandak M, Manwar N, Mani S, Mani A, Saini R, Malde R. Comparing Shear Bond Strength of Two Step vs One Step Bonding Agents on Ground Enamel and Dentin: An in vitro Study. Int J Experiment Dent Sci 2014;3(1):1-3.

Source of support: Nil

Conflict of interest: None

 
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