Cellular angiofibromas are rare benign mesenchymal neoplasms characterized by spindle cell component and numerous small vessels. They are commonly well-circumscribed, localized in the superficial soft tissues. The lesion is more frequently seen in the inguinoscrotal or vulvovaginal regions and occurs equally in men and women, and rarely involves oral cavity. Due to its clinical and histological similarity with other mesenchymal tumors, such as angiomyoma, hemangioma, lymphangioma and hemangiopericytoma, angiofibroma presents a diagnostic dilemma.

Very few cases of angiofibroma involving maxillofacial region have been reported in the literature. This case report involves cellular angiofibroma involving left buccal mucosa in a 23-year-old female patient. Following detailed clinical examination, radiological interpretation and histopathological diagnosis, surgical excision was performed. The patient was followed-up on a regular basis and was disease free.

Benign angiofibroma involving oral cavity is a rare tumor. There is a close resemblance of this tumor with other mesenchymal lesions and, thus, faces a diagnostic challenge. Surgical excision with a long-term followup gives good prognosis to this lesion—benign cellular angiofibroma.

Bokhari K, Manikandan L, Mohammad A, Shahul M, Bagi MA, Kota Z. Cellular Angiofibroma of the Buccal Mucosa: A Rare Case Report and Review of Literature. Int J Exper Dent Sci 2012;1(1):23-25.