International Journal of Experimental Dental Science

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Volume  10 (2021)
Volume  9 (2020)
Volume  8 (2019)
Volume  7 (2018)
Volume  6 (2017)
Volume  5 (2016)
Volume  4 (2015)
Volume  3 (2014)
Volume  2 (2013)
Volume  1 (2012)
Related articles

VOLUME 10 , ISSUE 1 ( January-June, 2021 ) > List of Articles

REVIEW ARTICLE

Effectiveness of Amniotic Membrane with Coronally Advanced Flap in the Treatment of Gingival Recession in Adult Patients: A Systematic Review

Ankita A Katkurwar, Swapna A Mahale

Keywords : Amnion membrane, Chronic periodontitis, Coronally advanced flap, Gingival recession, Placental membrane, Root coverage, Systematic review

Citation Information : Katkurwar AA, Mahale SA. Effectiveness of Amniotic Membrane with Coronally Advanced Flap in the Treatment of Gingival Recession in Adult Patients: A Systematic Review. Int J Experiment Dent Sci 2021; 10 (1):25-35.

DOI: 10.5005/jp-journals-10029-1223

License: CC BY-NC 4.0

Published Online: 11-08-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Aim and objective: To evaluate the effectiveness of amnion membrane on the clinical parameters when used in the treatment of Millers Class I and Class II gingival recession in chronic periodontitis patients along with coronally advanced flap (CAF). Data resources: Four databases MEDLINE (by PubMed), Cochrane database, EBSCO, and Google Scholar were explored to identify the studies in English up to April 2020. An additional hand search of relevant journals was also done. Two independent reviewers screened the retrieved articles using the particular inclusion criteria. Randomized control trials (RCTs) evaluating the effectiveness of amnion membrane with CAF in treatment of Millers Class I and Class II gingival recession in chronic periodontitis patients were included in the study. Outcome variables examined were recession width (RW), recession depth (RD), clinical attachment level (CAL), keratinized width of gingiva (KWG), probing pocket depth (PD), and gingival thickness (GT). Data were analyzed using Revman5.3 software. The mean differences and 95% confidence interval were used to illustrate the estimate of effect size. Study selection: Seven relevant articles were recognized for data procurement. One hundred and twenty patients with 244 gingival recession sites in total with an age range between 18 years and 55 years of participants were selected. There is an equal effect in both the groups for the RD reduction. For RW reduction, the result was in the favor of amnion membrane with CAF group, whereas for CAL gain, PD reduction, KWG gain, and GT gain results favored the different biomaterial other than amnion membrane but no statistical significant difference was found. Conclusion: Within the limitation of the study, it seems that the amnion membrane can be used successfully along with CAF to treat the gingival recession.

HTML PDF Share
  1. Zucchelli G, Mounssif I. Periodontal plastic surgery. Periodontol 2000 2015;68(1):333–368. DOI: 10.1111/prd.12059.
  2. Daprile G, Gatto MR, Checchi L. The evolution of buccal gingival recessions in a student population: a 5-year follow-up. J Periodontol 2007;78(4):611–614. DOI: 10.1902/jop.2007.060277.
  3. Serino G, Wennström JL, Lindhe J, et al. The prevalence and distribution of gingival recession in subjects with a high standard of oral hygiene. J Clin Periodontol 1994;21(1):57–63. DOI: 10.1111/j.1600-051x.1994.tb00278.x.
  4. Kassab MM, Cohen RE. The etiology and prevalence of gingival recession. J Am Dent Assoc 2003;134(2):220–225. DOI: 10.14219/jada.archive.2003.0137.
  5. Rehan M, Khatri M, Bansal M, et al. Comparative evaluation of coronally advanced falp using amniotic membrane and platelet-rich fbrin membrane in gingival recession: an 18-month clinical study,. Contemp Clin Dentis 2018;9(2):188–194. DOI: 10.4103/ccd.ccd_799_17.
  6. McGuire MK, Cochran DL. Evaluation of human recession defects treated with coronally advanced faps and either enamel matrix derivative or connective tissue. Part 2: histological evaluation. J Periodontol 2003;74(8):1126–1135. DOI: 10.1902/jop.2003.74. 8.1126.
  7. Aroca S, Keglevich T, Barbieri B, et al. Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: a 6-month study. J Periodontol 2009;80(2):244–252. DOI: 10.1902/jop.2009.080253.
  8. Zuhr O, Bäumer D, Hürzeler M. The addition of soft tissue replacement grafts in plastic periodontal and implant surgery: critical elements in design and execution. J Clin Periodontol 2014;41(Suppl. 15):S123–S142. DOI: 10.1111/jcpe.12185.
  9. Aroca S, Keglevich T, Nikolidakis D, et al. Treatmentof class III multiple gingival recessions: a randomized clinical trial. J Clin Periodontol 2010;37(1):88–97. DOI: 10.1111/j.1600-051X.2009.01492.x.
  10. Modaressi M, Wang HL. Tunneling procedure for root coverage using acellular dermal matrix: a case series. Int J Periodont Restorat Dent 2009;29(4):395–403.
  11. Esteves J, Bhat KM, Thomas B, et al. Efficacy of human chorion membrane allograft for recession coverage: a case series. J Periodontol 2015;86(8):941–944. DOI: 10.1902/jop.2014.140025c.
  12. Shieh AT, Wang HL, O'Neal R, et al. Development and clinical evaluation of a root coverage procedure using a collagen barrier membrane. J Periodontol 1997;68(8):770–778. DOI: 10.1902/jop.1997.68.8.770.
  13. Singh H, Singh H. Bioactive amnion as a guided tissue regeneration (GTR) membrane for treatment of isolated gingival recession. A case report. Indian J Dentis 2013;4(2):110–113. DOI: 10.1016/j.ijd.2012.12.007.
  14. Niknejad H, Peirovi H, Jorjani M, et al. Properties of the amniotic membrane for potential use in tissue engineering. Eur Cell Mater 2008;15:88–99. DOI: 10.22203/ecm.v015a07.
  15. Rana MP, Mehrotra N. Human amniotic membrane: hope in periodontal regeneration. Int J Sci Res (IJSR) 2016;5(4):564–569. DOI: 10.21275/v5i4.NOV162635.
  16. Mishra S, Singh S. Human amniotic membrane: can it be a ray of hope in periodontal regeneration? Indian J Res 2014;3(9):118–121.
  17. Sharma A, Komal Y. Amniotic membrane–a novel material for the root coverage: a case series. J Indian Soc Periodontol 2015;19(4):444–448. DOI: 10.4103/0972-124X.154166.
  18. Liberati A, Altman DG, Tetzlaff J, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 2009;62(10):e1–e34. DOI: 10.1016/j.jclinepi.2009.06.006.
  19. Moher D, Shamseer L, Clarke M, et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst Rev 2015;4(1):1. DOI: 10.1186/2046-4053-4-1.
  20. Higgins J, Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1. 0. The Cochrane Collaboration; 2011. Available from: http://www.cochrane-handbook.org.
  21. Manager RR, The Nordic Cochrane Centre, the Cochrane Collaboration. Version 5.3. Copenhagen: Computer Program; 2014.
  22. Cheng GL, Fu E, Tu YK, et al. Root coverage by coronally advanced flap with connective tissue graft and/or enamel matrix derivative: a meta-analysis. J Period Res 2015;50(2):220–230. DOI: 10.1111/jre.12199.
  23. Ghahroudi AA, Khorsand A, Rokn AR, et al. Comparison of amnion allograft with connective tissue graft for root coverage procedures: a double-blind, randomized, controlled clinical trial. J Int Acad Periodontol 2013;15(4):101.
  24. Chakraborthy S, Sambashivaiah S, Kulal R, et al. Amnion and chorion allografts in combination with coronally advanced flap in the treatment of gingival recession: a clinical study. J Clin Diagnos Re 2015;9(9):ZC98. DOI: 10.7860/JCDR/2015/12971.6572.
  25. Lafzi A, Abolfazli N, Faramarzi M, et al. Clinical comparison of coronally-advanced flap plus amniotic membrane or subepithelial connective tissue in the treatment of Miller's class I and II gingival recessions: a split-mouth study. J Dent Res, Dent Clin, Dent Prosp 2016;10(3):162. DOI: 10.15171/joddd.2016.026.
  26. Agarwal SK, Jhingran R, Bains VK, et al. Patient-centered evaluation of microsurgical management of gingival recession using coronally advanced flap with platelet-rich fibrin or amnion membrane: a comparative analysis. Eur J Dentis 2016;10(1):121. DOI: 10.4103/1305-7456.175686.
  27. Jain A, Jaiswal GR, Kumathalli K, et al. Comparative evaluation of platelet rich fibrin and dehydrated amniotic membrane for the treatment of gingival recession-a clinical study. J Clin Diagnos Res 2017;11(8):ZC24. DOI: 10.7860/JCDR/2017/29599.10362.
  28. Mahajan R, Khinda P, Shewale A, et al. Comparative efficacy of placental membrane and Healiguide™ in treatment of gingival recession using guided tissue regeneration. J Indian Soc Periodontol 2018;22(6):513. DOI: 10.4103/jisp.jisp_88_18.
  29. Chopra P, Kassal J, Masamatti SS, et al. Comparative evaluation of clinical efficacy of coronally advanced flap alone and in combination with placental membrane and demineralized freeze-dried bone allograft in the treatment of gingival recession. J Indian Soc Periodontol 2019;23(2):13. DOI: 10.4103/jisp.jisp_308_18.
  30. Irfan M, Mehta T, Kumar S, et al. Comparative clinical study of coronally positioned flap with and without dehydrated amnion allograft in the treatment of gingival recession. J Dent Health Oral Disord Ther 2017;8(3):00281. DOI: 10.15406/jdhodt.2017.08.00281.
  31. George SG, Kanakamedala AK, Mahendra J, et al. Treatment of gingival recession using a coronally-advanced flap procedure with or without placental membrane. J Investigat Clin Dentis 2018;9(3):e12340. DOI: 10.1111/jicd.12340.
  32. Blumenthal NM. The use of collagen membranes to guide regeneration of new connective tissue attachment in dogs. J Periodontol 1988;59(12):830–836. DOI: 10.1902/jop.1988.59.12.830.
  33. Wang HL, Al-Shammari KF. Guided tissue regeneration--based root coverage utilizing collagen membranes: technique and case reports. Quintessence Int 2002;33(10):715–721.
  34. Pakkala T, Virtanen I, Oksanen J, et al. Function of laminins and laminin-binding integrins in gingival epithelial cell adhesion. J Periodontol 2002;40(7):709–719. DOI: 10.1902/jop.2002.73.7.709.
  35. Takashima S, Yasuo M, Sanzen N, et al. Characterization of laminin isoforms in human amnion. Tissue and Cell 2008;40(2):75–81. DOI: 10.1016/j.tice.2007.09.001.
  36. Kaur J, Bathla SC. Regenerative potential of autologous platelet-rich fibrin with and without amnion membrane in the treatment of grade-II furcation defects: a clinicoradiographic study. J Indian Soc Periodontol 2018;22(3):235. DOI: 10.4103/jisp.jisp_119_18.
  37. Kiani YF, Moloudi F, Nozari HB, Comparison of amnion membrane with Bio-Gide in conjunction with Bio-Oss in treatment of intrabony periodontal defects. Sadra Medical Sciences Journal 2013;1(4):215–232
  38. Alghamdi H, Babay N, Sukumaran A. Surgical management of gingival recession: a clinical update. Saudi Dent J 2009;21(2):83–94. DOI: 10.1016/j.sdentj.2009.07.006.
  39. Chambrone L, Chambrone D, Pustiglioni FE, et al. The influence of tobacco smoking on the outcomes achieved by root-coverage procedures: a systematic review. J Am Dent Associat 2009;140(3):294–306. DOI: 10.14219/jada.archive.2009.0158.
  40. Chopra A, Thomas BS. Amniotic membrane: a novel material for regeneration and repair. J Biomim Biomater Tissue Eng 2013; 18:106.
  41. Cardaropoli D, Cardaropoli G. Healing of gingival recessions using a collagen membrane with a hemineralized xenograft: a randomized controlled clinical trial. Int J Periodontics Restorative Dent 2009;29(1):59–67.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.