International Journal of Experimental Dental Science

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VOLUME 2 , ISSUE 2 ( July-December, 2013 ) > List of Articles

RESEARCH ARTICLE

Clinical and Microbiological Evaluation of Chlorine Dioxide Based Mouthwash and Toothpaste in Periodontitis Patients along with Combination of Nutritional Dietary Supplement of CoQ10

Citation Information : Clinical and Microbiological Evaluation of Chlorine Dioxide Based Mouthwash and Toothpaste in Periodontitis Patients along with Combination of Nutritional Dietary Supplement of CoQ10. Int J Experiment Dent Sci 2013; 2 (2):98-103.

DOI: 10.5005/jp-journals-10029-1049

Published Online: 00-12-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Aim

The present study to assess and compare the clinical and antimicrobial effects of sodium chlorite based toothpaste and mouthwash in periodontitis patients along with combination of nutritional dietary supplement of CoQ10 with conventional based toothpaste and mouthwash without sodium chlorite.

Materials and methods

A total 100 generalized chronic periodontitis patient between the ages of 18 and 55 years were enrolled in the study and divided under four categories. Clinical and microbiological parameters were recorded prior to phase 1 therapy; and subjects were put on different oral hygiene regime with chlorine dioxide based and conventional dentifrice and mouthrinse. CoQ10 was also provided in both the groups as nutritional dietary supplement. At 2nd and 4th month post-phase 1 therapy subjects were re-evaluated.

Results

The results of this study showed that there was significant decrease in clinical, and microbiological parameters from baseline to 4 months in both the groups (p < 0.01). The subjects under groups using sodium chlorite based toothpaste and mouthwash with dietary supplement of CoQ10 showed a highly significant reduction to all the parameters as compared to subjects under groups using a conventional dentifrice and mouthrinse.

Conclusion

Thus, we can conclude that long-term regular use of chlorine dioxide based products along with nutritional supplement of CoQ10 is more beneficial than conventional toothpaste and mouthrinse.

How to cite this article

Mani S, Mani A, Saini R. Clinical and Microbiological Evaluation of Chlorine Dioxide Based Mouthwash and Toothpaste in Periodontitis Patients along with Combination of Nutritional Dietary Supplement of CoQ10. Int J Experiment Dent Sci 2013;2(2):98-103.


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  1. Oral sex, oral health and orogenital infections. J Global Infect Dis 2010;1:57-62.
  2. Periodontal diseases: a risk factor to cardiovascular disease. Ann Card Anaesth 2010;13:159-161.
  3. Dental air force home dental cleaning system: A revolutionary oral hygiene device to prevent systemic diseases caused by periodontal infection. Int J Med Res Health Sci 2013; 2(3):431-438.
  4. Biofilm: a dental microbial infection. J Nat Sc Biol Med 2011;2:71-75.
  5. Microbial flora on toothbrush—at greater risk. Ann Nigerian Med 2010;4:31-32.
  6. Vitamins and periodontitis. J Pharm Bioall Sci 2011;170.
  7. Elevated hydroperoxide levels and antioxidant patterns in Papillon Lefevre syndrome. J Periodontol 2001;72: 1760-1766.
  8. Oxidative injury and inflammatory periodontal diseases: the challenge of antioxidants to free radicals and reactive oxygen species. Crit Rev Oral Biol Med 1999;10:458-476.
  9. Management of periodontitis with oral-care products. Compend Contin Educ Dent 1994;15: 740-746.
  10. Reduction of bleeding on probing with oral care products. Compend Contin Educ Dent 1995;16: 188-196.
  11. Role of Coenzyme Q10 as an antioxidant and bioenergizer in periodontal disease. Ind J Pharmacol 2010;42(6):334-337.
  12. Deficiency of coenzyme Q in gingival tissue from patients with periodontal disease. Int J Vitam Nutr Res 1973;43:84-92.
  13. Deficiency of coenzyme Q10 in gingival tissue from patients with periodontal disease. Proc Nat Acad Sci USA 1971;68:2332-2335.
  14. Bioenergetics in clinical medicine. II. Adjunctive treatment with coenzyme Q in periodontal treatment. Res Commun Chemic Path Pharm 1975;12:111-124.
  15. Study of CoQ10-enzymes in gingiva from patients with periodontal disease and evidence for a deficiency of coenzyme Q10. Proc Natl Acad Sci USA 1974;71:1456-1460.
  16. Clinical effect of coenzyme 10 on periodontal disease; evaluation of oxygen utilization in gingiva by tissue reflectance spectrophotometry. In: Shizukuishi S, Hanioka T, Tsunemitsu A, editors. Biomedical and clinical aspects of Coenzyme Q. Amsterdam: Elsevier 1986;5:359-368.
  17. Therapy with Coenzyme Q10 for patients with periodontal disease. 1. Effect of Coenzyme Q10 on subgingival micro-organisms. J Dent Health 1993;43:659-666.
  18. Bioenergetics in clinical medicine. VI. Adjunctive treatment of periodontal disease with CoQ10. Res Commun Chem Path Pharmac 1976;14:715-719.
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