International Journal of Experimental Dental Science

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VOLUME 3 , ISSUE 1 ( January-June, 2014 ) > List of Articles

RESEARCH ARTICLE

Study on C-reactive Protein in Periodontal Diseases: Estimation and Correlation in Health, Gingivitis and Periodontitis and its Assessment after Scaling and Root Planing

Citation Information : Study on C-reactive Protein in Periodontal Diseases: Estimation and Correlation in Health, Gingivitis and Periodontitis and its Assessment after Scaling and Root Planing. Int J Experiment Dent Sci 2014; 3 (1):4-7.

DOI: 10.5005/jp-journals-10029-1059

Published Online: 01-06-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background

Periodontitis is associated with elevated levels of systemic inflammatory biomarker C-reactive protein (CRP). This study is outlined to determine and correlate the C-reactive CRP level in health, gingivitis and periodontitis and to assess the CRP values after complete scaling and root planing.

Materials and methods

A total of 60 systemically healthy subjects enrolled in the study. Out of which 20 subjects each categorized under three groups, i.e. periodontally healthy, gingivitis and periodontitis. Clinical parameters and serum CRP is recorded at the baseline 15th and 30th day.

Results

Patients with chronic periodontitis had statistically significant elevations in serum CRP levels as compared to gingivitis and absence of detection of serum CRP level in health group. Results showed a highly significant change in clinical parameters and serum CRP with regard to improvement in the gingival inflammation and reduced bleeding on probing and plaque accumulation from the baseline when compared to the 15th day and 30th day.

Conclusion

A correlation exists between the periodontal disease and CRP, as the periodontal disease regresses the value of CRP lowers down significantly. Nonsurgical periodontal treatment, i.e. scaling and root planing was effective in reducing the levels of serum CRP.

How to cite this article

Saini R. Study on C-reactive Protein in Periodontal Diseases: Estimation and Correlation in Health, Gingivitis and Periodontitis and its Assessment after Scaling and Root Planing. Int J Experiment Dent Sci 2014;3(1):4-7.


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