The study was undertaken with the objective of evaluating the effect of probiotics on Candidal adherence on different heat cure denture base materials in maxillofacial patients. After Acralyn-H, Pyrax heat cure denture base resin showed less adherence to heat followed by Dental Products of India (DPI) heat cure denture base resin. Candidal cell count was significantly reduced on different heat cure denture base materials after giving probiotics to maxillofacial patients. The heat cure polymethylmethacrylate (PMMA) specimens were fabricated respectively, 60 samples in total, 30 samples before giving probiotics, and 30 samples after giving probiotics. The adherence of yeast on the tissue surface of the specimens was given prime consideration as the adherence is seen more on the rough surface topographies. The samples were inoculated with Candida albicans at 37°C for 24 hours and incubated for 48 hours followed by examination of the yeast cells using light microscopy. The Candidal cell count on different specimens was compared before and after giving probiotics.
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