Background: Cushing's syndrome is a debilitating endocrine disorder comprising signs and symptoms due to prolonged exposure to cortisol. It is characterized by excessive cortisol levels in the blood, which may be the result of various causes, such as tumors of pituitary glands, tumors arising elsewhere in the body (ectopic adrenocorticotropic hormone-producing tumors), or exogenous causes, such as prolonged intake of steroids (known as Cushing's habitus). Aim: This article is a case report on the management of a patient with Cushing's habitus, presenting with recurrent oral ulcers as one of the manifestations. Case report: A 25-year-old patient diagnosed with Cushing's habitus came to the department with complaint of recurrent ulcers on the tongue and lips since 6 months. These ulcers were unresponsive toward conventional therapies, such as amlexanox and steroids. Conclusion: Due to the unique history presented by the patient and the persistence of recalcitrant ulcers, an immunomodulator was prescribed. This drug prevented the recurrence of the oral ulcers. Clinical significance: Various manifestations of Cushing's disease include metabolic, cardiovascular, and endocrinal abnormalities, to mention a few. Prevalence of dental manifestations is rare, oral ulcers being among the few. These oral ulcers require special consideration since the underlying pathogenesis of the ulcers is very different. This article describes the management of such ulcers in Cushing's habitus using an immunomodulator.